A micro-epidemiological analysis of febrile malaria in Coastal Kenya showing hotspots within hotspots

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A micro-epidemiological analysis of febrile malaria in Coastal Kenya showing hotspots within hotspots

Malaria transmission is spatially heterogeneous. This reduces the efficacy of control strategies, but focusing control strategies on clusters or 'hotspots' of transmission may be highly effective. Among 1500 homesteads in coastal Kenya we calculated (a) the fraction of febrile children with positive malaria smears per homestead, and (b) the mean age of children with malaria per homestead. These...

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BACKGROUND Infectious diseases often demonstrate heterogeneity of transmission among host populations. This heterogeneity reduces the efficacy of control strategies, but also implies that focusing control strategies on "hotspots" of transmission could be highly effective. METHODS AND FINDINGS In order to identify hotspots of malaria transmission, we analysed longitudinal data on febrile malar...

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Effect of transmission intensity on hotspots and micro-epidemiology of malaria in sub-Saharan Africa

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ژورنال

عنوان ژورنال: eLife

سال: 2014

ISSN: 2050-084X

DOI: 10.7554/elife.02130